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PGTM

PGTM

PGTM

Preimplantation Genetic Testing for Monogenic disorders (PGTM) is used during IVF to test embryos for specific genetic conditions before implantation, ensuring that only embryos free of particular genetic disorders are selected for transfer

>When is PGTM needed

When is PGTM needed?

PGTM is used to screen embryos for specific inherited genetic diseases before implantation. It's recommended for couples with a family history of a genetic disorder or those who are carriers of a recessive disease.

embryos
Family history of a genetic disorder

Family history of a genetic disorder

When a couple has a known genetic condition in their family.

Carrier status

Carrier status

If one or both partners are carriers of a recessive genetic disease.

Previous affected child

Previous affected child

When a couple has already had a child with a genetic disorder.

Specific genetic marker screening

Specific genetic marker screening

For instance, HLA typing for a sick child requiring a transplant.

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Procedure

IVF Cycle: The process begins with standard IVF, involving ovarian stimulation, egg retrieval, and fertilization.

Embryo Biopsy: A small number of cells are removed from the developing embryo (blastocyst stage).

Genetic Analysis: The removed cells are analyzed for the specific genetic mutation associated with the disorder.

Embryo Selection: Embryos without genetic mutation are selected for transfer.

Embryo Transfer: Healthy embryos are transferred to the uterus.

Pregnancy Test: A pregnancy test is taken to confirm implantation.

Ready to take next step?

Schedule a consultation with our expert team at MMC IVF. We are here to provide personalized care and support